High Density (HD) endocardial catheter mapping is used for precise localization and selective ablation of arrhythmogenic substrates in the heart. By using the myocyte specific 1064nm laser wavelength HD lasermapping allowed for monitoring of lesion formation in the myocardial wall during laser application. With timely stop of HD lasermapping guided ablation the lesion is limited to the myocardial wall sparing adjacent healthy myocardium and mediastinal structures including the esophagus, lungs, vagus etc. from thermal injury. HD lasermapping guided ablation is performed under normothermic conditions. It is a low power – short duration procedure. With its unique safety and efficacy characteristics it is more than just a viable alternative to traditional ablation techniques for ablation of cardiac tachyarrhythmias. With its large potential for further development e.g., artificial intelligence, and with its request for design to cost (DTC) for competitive products, HD lasermapping is unique and has a high potential for becoming an all pervasive catheter ablation procedure.
Keywords: Catheter mapping; Catheter ablation; High-Density Lasermapping; Laser; Tachyarrhythmias.
Citation: Weber, H. et al., (2026). High-Density Lasermapping Guided Catheter Ablation – Development and Application.. I J cardio & card diso; 7(1):1-14. DOI : https://doi.org/10.47485/2998-4513.1052