Unexpected bleeding following childbirth remains the leading cause of maternal mortality worldwide. In 2023, an estimated 260,000 women died during pregnancy, delivery, or the postpartum period—equivalent to nearly one maternal death every two minutes (1). Since the launch of one of the pioneering global initiatives to reduce maternal and child mortality in 1987, maternal mortality has declined by approximately 40% since 2000 (2). However, progress remains insufficient. The recently published Consolidated Guidelines for the Prevention, Diagnosis, and Treatment of Postpartum Hemorrhage (3) introduce new strategies for predicting maternal mortality and severe morbidity, aiming to contribute to the global target of 70 maternal deaths per 100,000 deliveries. Coagulopathies, both acquired and inherited represent a significant risk for development of postpartum hemorrhage. This perspective aims to examine the affordability and implementation readiness of countries contributing most significantly to the persistently high maternal mortality burden.
Keywords: Postpartum hemorrhage, coagulopathy reversal, patients’ blood management, risk factors for massive blood loss, protocols for bleeding management.
Citation: Schmiedl, J. et al., (2026). Optimizing Coagulopathy Management in Postpartum Hemorrhage : Preventive and Reversal Strategies for Resource-Limited Settings. J Medical Case Repo 8(2):1-11.
DOI : https://doi.org/10.47485/2767-5416.1148












