Paulraj S1*, Balamurugan G2 and Ramalingam3

Osteosarcoma is a rare condition with a complex treatment commonly reported in teen age children. With the present standard treatment protocols, one could achieve up to 76% overall survival rate in any case of localized osteosarcoma. By attenuating the major risk factor like open biopsy that is routinely followed in osteosarcoma cases, the failure incidents could be reduced considerably. Although good number of research findings provide sufficient information on the serious risks involved in opting for open biopsy and, on the availability of safer biopsy methods like core needle biopsy, the open biopsy is being followed as a first-line standard treatment protocol for osteosarcoma in many cases. The immediate need for abandoning the open biopsy method as a fist-line application in the treatment protocol of osteosarcoma is discussed.

Keywords: Contraindication; Biopsy risks; Bone cancer; Tumor seeding; Metastasis.

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Citation: Paulraj, S. et al., (2026). First-Line Application of Open Biopsy Method in Osteosarcoma Prognosis – The Contraindications. J Sur & Surgic Proce.,4(1):1-9. DOI : https://doi.org/10.47485/3069-8154.1027