Eduardo Miguez Bastos da Silva1, Mariana Sato de Bustamante Monteiro2, Paulo Sergio Rangel Cruz da Silva3 and Maria Inês Bruno Tavares4*

The major understanding of molecular and cells basis of pathophysiological states has allowed the development of new drugs. However, this required a new and complex release system. Polymers offer the most promising way for controlled release and polymeric nanocomposite is a new perspective in the pharmaceutical area. NMR techniques employed supply a vision of the molecular dynamic processes and give information of structural level. NMR experiments like, inversion-recovery pulse sequence, have the advantage of detecting intermolecular interaction between a drug and polymeric nanocomposite matrix.

Keywords: nanocomposites, PCL, Nevirapine, NMR

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