H NMR in Solution of Nanocomposites from Polycaprolactone – Nevirapine
H NMR in Solution of Nanocomposites from Polycaprolactone – Nevirapine
Eduardo Miguez Bastos da Silva1, Mariana Sato de Bustamante Monteiro2, Paulo Sergio Rangel Cruz da Silva3 and Maria Inês Bruno Tavares4*
The major understanding of molecular and cells basis of pathophysiological states has allowed the development of new drugs. However, this required a new and complex release system. Polymers offer the most promising way for controlled release and polymeric nanocomposite is a new perspective in the pharmaceutical area. NMR techniques employed supply a vision of the molecular dynamic processes and give information of structural level. NMR experiments like, inversion-recovery pulse sequence, have the advantage of detecting intermolecular interaction between a drug and polymeric nanocomposite matrix.
Journal of Nanotechnology and Nano Science Research (JNNSR) is a peer-reviewed, open-access journal dedicated to publishing high-quality research that advances scientific knowledge and clinical practice.