Rationale: Neuroendocrine tumors are rare distinct neoplasms with varying incidence. Neuroendocrine tumors are mostly affecting the gastrointestinal tract. Carcinoid tumors are considered a synonymous name for neuroendocrine tumors. Rheumatic heart disease is a major differential for carcinoid disease. Patient concerns: A young-aged housewife female patient presented to physician outpatient clinic for cardiovascular follow-up for abdominal tumors with aortic valve replacement. Diagnosis: Neuroendocrinal tumor-inducing severe aortic regurgitation with low-ejection fraction stable heart failure. Interventions: Echocardiography, aortic valve replacement, and electrocardiography. Outcomes: Diverse outcome post-aortic valve replacement had happened. Lessons: Valvular heart disease may be occurring with carcinoid tumors but the wrong diagnosis for the rheumatic heart is common. The fixation of low myocardial ejection fraction with absent heart failure is an innovative interesting issue. The absence of the above symptoms and symptoms of heart failure after aortic valve replacement despite low ejection fraction and the still present tumor may carry diverse outcomes.
Keywords : Neuroendocrinal tumor, Carcinoid, Aortic regurgitation with low-ejection fraction, Stable heart failure, Valvular heart disease.