Objective: Twin Anemia Polycythemia Sequence is a serious complication of monochorionic twin pregnancy, however in dichorionic pregnancy is an uncommon complication. Although this is extremely rare, we would like to emphasize the need for the medical community to acknowledge that in some cases, a sequence of anemia and polycythemia may occur in dichorionic twins, as well as other blood flow imbalances and we should always take this into consideration.
Data Sources: We carried out a systematic search in multiple databases, including PubMed, Scopus, and Medline/Embase from a time period involving the last 5 years from 2024.
Study Selection: Only data from case reports were found and therefore included for the analysis.
Data Extraction and Synthesis: The subject-related articles were processed according to Preferred Reporting Items in Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We evaluated five case reports.
Results: Two of the five clinical cases fully met both the prenatal and postnatal criteria for TAPS. The remaining cases partially met these requirements. Tests to determine zygosity are extremely important in the case of dizygotic twins, as they allow for increased vigilance in detecting complications at an early stage of twin pregnancy.
Conclusions: With an understanding of the type of zygosity in dichorionic twin pregnancies, it becomes possible to anticipate complications typical of monochorionic pregnancies. This information is essential and may become a valuable tool in managing and preventing complications in both antenatal and neonatal care.
Keywords: twin anemia-polycythemia sequence; TAPS; dichorionic pregnancy
Citation: Martyna D. et.al. (2025). Unusual Twin Anemia-polycythemia Sequence in a Dichorionic Diamniotic Pregnancy. A Case Report and Systematic Review. J Medical Case Repo 7(4):1-10.
DOI : https://doi.org/10.47485/2767-5416.1136