ONWURAH O.W, AJUBA C.I, ANOKWUTE M.U, NKEMJIKA U.N, NWACHUKWU E.P and EZE C.G

Haemoglobin genotypes are very important in the sub-Saharan African, it aids in assessing the health of an individual. About 85 million people are carriers of different Hb genotype variants in Sub-Saharan Africa. The aim of this study is to establish the echelon of haemoglobin genotype variants in Anambra state Southeast Nigeria from 2005 to 2019. A total number of 50,169 retrospective records of haemoglobin genotype results were analyzed using the Statistical Package for Social Sciences (SPSS) computer software. The study showed that 74.65% were Hb genotype AA, 23.16% were Hb genotype AS, 0.26% were Hb genotype AC, 1.84% were Hb genotype SS and 0.09% were Hb genotype SC. The female subjects had higher frequency distributions in Hb genotype AA, AS, and SC, than the male. The Hb genotype AA ranked the highest Hb genotype variants, followed by Hb genotype AS, SS, AC and lastly SC in Anambra state, Southeast Nigeria.

Keywords: Echelon, Haemoglobin genotype, Anambra state

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